Linux Font size becomes very small after changing resolution - ThinkStation E30, S30, D30, C30
If the display resolution is changed using the Nvidia X server settings to 1024x768 or 1280x1024 or 166x1200 and Then apply and save to X Comfit file, the font size may become small.
The above symptom is associated with, but not limited to, the following systems:
ThinkStation E30, S30, D30, C30
Red Hat Enterprise Linux 6.0
Use the X configuration option mentioned in the previous comment, or by hard coding a specific DPI value in GNOME, either by editing the GNOME configuration key /desktop/gnome/font_rendering/dpi in gconf-editor, or by clicking on the "Details" button in the "Font" tab of the "Appearance" control panel.